Precision Health

Revolutionary advances in genomics, gene editing, and big data have given us the ability to understand, prevent, detect, diagnose, and treat disease with extraordinary levels of precision.

At the micro level, Duke’s Charles Gersbach, PhD, and colleagues are pioneering the use of genomic technologies such as CRISPR to manipulate specific regions of the genome and open whole new targets of opportunity for treating a wide range of diseases, including genetic disorders, neurodegeneration, and cancer.

And at the population level, Svati Shah, MD, MHS, spearheads the Duke Center for Precision Health, which bridges the worlds of research and patient care by integrating genomic data with clinical operations. Shah and her colleagues recently launched OneDukeGen, a large-scale research study that aims to collect and analyze DNA and other data from 100,000 Duke Health patients, generating an invaluable repository that will inform new research on numerous diseases and conditions.

 Across Duke Health, researchers are pushing the boundaries of what is possible to tailor health care for each individual.