Samuel L. Katz, MD, described himself as merely a “young, enthusiastic, and naïve pediatrician” who “came along at the right time, in the right laboratory, with the right colleagues.” This is a remarkably humble reframing of the accomplishments of the pioneering virologist, pediatrician, and chairman emeritus and Wilburt C. Davison Professor Emeritus of Pediatrics at Duke University School of Medicine.