What if we could disable the defense mechanisms that enable cancer cells to evade treatment, or even control their genes to prevent them from developing into tumors in the first place? Can we enhance our brain’s ability to forestall damage from Alzheimer’s disease and other neurodegenerative conditions? Is it possible to develop a vaccine for everything?
Yvonne Mowery, MD, PhD, Butler Harris Assistant Professor in Radiation Oncology, is one of many physician-scientists at Duke who credits the Duke University School of Medicine’s Strong Start Program for her career growth.
Michael Boyce, PhD, associate professor of biochemistry, never expected to be studying the lungs. He is an expert in glycobiology—the intricate mechanisms behind how sugars attach to proteins, and the role these sugars play in sending signals that influence cell biology, organ function, and more.
With sepsis, time is of the essence. Left untreated, the illness—a runaway immune response to infection—can quickly become life-threatening. Duke hospital medicine physician Cara O’Brien, MD, is partnering with the Duke Institute for Health Innovation to lead a multidisciplinary team of physicians, nurses, and biostatisticians that is using data science to rapidly identify at-risk patients, speed treatment, and improve outcomes.
Through the Regeneration Next Initiative, Duke researchers are gaining insights into how to stimulate heart muscle to regrow after injury.
Researchers at the Duke Cancer Institute are teaming up with several other institutions to develop a fluorescent dye that is injected into cancerous tumors and lights up when viewed under a special camera. This allows surgeons to see if residual cancer remains after the tumor has been removed.
Why do perfectly good cancer treatments suddenly stop working? Researcher and lymphoma survivor Kris Wood is finding answers.
“One day, patients will have access to regenerative medicine treatments that will circumvent the complications of organ donation,” says Sharlini Sankaran, PhD, executive director of Duke’s Regeneration Next Initiative. “We will be able to use our bodies’ own innate repair mechanisms to eliminate the wait time, cost, and limited supply of organ transplantation. Instead of transplanting organs, we will know how to repair our own.”
The fortified Toyota Land Cruiser slipped and bounced in the muddy hollows of the rain-drenched Mongolian steppe. The driver, a native Mongolian man named Inka who spoke little English, slowly engineered the vehicle along what just two days earlier was a dusty pair of dirt tracks.
The United States has one of the highest rates of preterm birth—up to 10 percent of all pregnancies—in the world. And many pregnancy complications, such as pre-eclampsia, which contributes to preterm birth, are associated with abnormal placental development.